Sharva Hiremath is a PhD student in the Electrical and Computer Engineering Department at North Carolina State University. He received his Bachelors in Electronics & Communication Engineering from Manipal Institute of Technology (India) and his M.S. in Electrical Engineering from NC State. His research focuses on the use of image analysis techniques to estimate gene expression in Drosophila melanogaster. His research interests are computer vision, machine learning, and digital signal processing.
Analysis of Dorsal gradient system in Drosophila melanogaster: The Dorsal protein plays a vital role in the Differentiation (patterning) of cells in Drosophila. The accurate measurement of the dorsal gradient is important to gain a better system level understanding of the developmental biology, signaling dynamics and gene regulation. My work focuses on using computer vision and image processing techniques to quantify the spatiotemporal behavior of dorsal gradient and build predictive models using mathematical modelling of the parameters involved in this process. This is an ongoing project being conducted with a collaboration with The Reeves Lab (Dr. Gregory Reeves).